Stainless-Steel Performance.
Single-Use Agility.

ABEC’s CSR platform delivers unrivaled performance, scale, and flexibility for single use bioprocessing.  Carrying over the proven design and performance of stainless steel, CSR custom vessels have unlocked new benchmarks in productivity.

Process transfer and scaling ahead of the rest—expect consistent performance when moving optimized cell culture processes from stainless steel to single-use and across scaled-up working volumes.

Operational efficiency unmatched in single-use—CSR operates at the largest scale in the industry and can be tailored to optimize your unique process conditions.  Use your facility more effectively, with higher capacity and yields.

CSR SYSTEM APPLICATIONS

Culture Vessels

  • Bioreactors for mammalian cell culture, up to 6000L working volume
  • Microbial fermenters up to 1000L

Solutions & Mixing Vessles

  • GenMix systems with up to 7500L working volumes
  • 10:1 turndown volume flexibility for low titer continuous processes
  • Full integration with external filtration systems, pumps, and sensors
  • Suitable for media and buffer preparation, pooling, viral inactivation, and more

Large Volume Solution Hold (LVSH)

  • Accommodate multiple media or buffers, each up to 5000L
  • Exclusive horizontal design enables stable fluid delivery at high flow rates while reducing tubing run lengths
  • Self-deploying disposable container bag minimizes operator handling

Ultrafiltration/Diafiltration (UF/DF)

  • Fully single-use flow paths for rapid batch-to-batch and campaign-to-campaign changeovers
  • 1.5″ flow path supports up to 260 L/min flow path
  • Customizable for specific applications and filter types, including cassettes and hollow fiber

CSR Flexible Manufacturing Platform (FMP)

  • Based on scalable CSR single-use and core stainless-steel systems
  • Enables twice the product output from bioreactor to bulk fill
ABEC CSR® Single-Use Systems for Maximum Flexibility & Productivity

Engineered around proven stirred tank fundamentals – maintaining cylindrical geometry, optimized aspect ratios, and high power per volume – CSR single use bioreactors provide best-in-class oxygen transfer and mixing performance.  Also supporting high-density and intensified processes, the ABEC CSR platform reliably scales from pilot to commercial production.

Consistent engineering design across volumes minimizes scale-up uncertainty and the cycle of optimization and revalidation.  With predictable performance from 50L to 6000L, ABEC single-use bioreactors are designed for scale continuity, not just volume increases.

ABEC has been proudly partnering with customers in biopharma for over 50 years, supporting critical manufacturing operations.  ABEC currently enables more than 400,000 L of single-use capacity for GMP manufacturing, with multiple production facilities to reduce lead times and provide redundancy.  Additionally, ABEC sources from non-proprietary suppliers to give more transparency into our supply chain and avoid the risk of relying on a single supplier.

Flexible by design, ABEC CSR solutions fit your upstream and downstream requirements – from process and operating conditions to facility considerations, while delivering best-in class performance and scale.  Optimize for particular cell lines, accommodate facility space constraints and access, and integrate into your plant control architecture. 

Supply Chain CSR® Single-Use Systems

Replace lower performing and smaller capacity single-use systems with more productive, larger working volume systems.  Meeting demand with fewer annual batch runs, fewer equipment systems, and greater operational efficiency – CSR systems are transforming the economics of single-use manufacturing.

PROVEN TO DELIVER

CUSTOM SCALABILTY

Cell Culture Bioreactors
Microbial Fermenters
General Mixing
Buffer Hold Storage
Capactiy Supplied

Contact Us